Myocyte相关论文
Nicorandil enhances Na+/Ca2+ exchanger activity via guanylate cyclase activation in cardiac ventricu
Aim: Nicorandil exhibited cardioprotective and antiarrhythmic effects during the process of ischemia/reperfusion in hear......
AIM: To determine the possible role of pH in mediating activation of p38 mitogen-activated protein kinase (MAPK) and the......
Virus infection and subsequent myocardial damageand repairing were regarded as important aspects inthe pathogenesis of ......
Role of Bradykinin on Left Ventricular Remodeling and Cardiac Function after Myocardial Infarction i
Objectives To investigate the influences of bradykinin (BK) on hemodynamics, left ventricular hypertrophy and interstiti......
Cellular Retinol-Binding Protein-1 Is Transiently Expressed in Myocardial Infarction Tissue of Rat M
Objectives To investigate the expression state of cellular retinol-binding protein-1 (CRBP-1) in myocardial infarction (......
Effects of valsartan on matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-
Background To observe the effects of valsartan on matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix meta......
The cardioprotection induced by lipopolysaccharide involves phosphoinositide 3-kinase/Akt and high m
Objective:The mechanisms by which lipopolysaccharide(LPS)pretreatment induces cardioprotection following ischaemia/reper......
Intracellular signaling networks mediate specific features of cardiac remodeling in pathologically stressed hearts.Prote......
Effects of Ginkgolide B on action potential and calcium, potassium current in guinea pig ventricular
AIM: To investigate the effect of Ginkgolide B (GB) on action potential (AP) , delayed rectifier potassium current (IK)......
The Effectand Mechanism of Forsinopril on Ventricular Hypertrophy of SHR and Left Ventricular Pressu
The effects and mechanism of long term angiotensin converting enzyme inhibitor (ACEI) Forsinopril on left ventricular h......
To observe the regulation of platelet-derived growth factor (PDGF) receptor-p in myocyte stimulated by angiotensin Ⅱ (A......
Activation of extracellular signal-regulated kinase during silibinin-protected,isoproterenol-induced
Aim:To investigate the mechanism of silibinin-protected isoproterenol-inducedapoptosis in rat cardiac myocytes.Methods:......
Regulation of Content of Malondialdehyde by Siqi Decoction via Increasing Activity of Superoxide Dis
Effect of Siqi decoction on myocardial ischemia is to prevent cardiac myocyte membrane from damage associated with oxyge......
Effects of Xinjining(心悸宁) Extract on Inward Rectifier Potassium Current in Ventricular Myocytes of G
Objective:To study the effect of Xinjining extract(心悸宁,XJN) on inward rectifier potassium current(I_(K1)) in ventricu......
Effects of endothelin-1 on differentiation of cardiac myocyte induced from rabbit bone marrow stroma
Background Cardiomyocyte transplantation for the therapy of myocardial ischaemia is being paid close attention. However,......
Objective Adipose-derived stem cells(ADSCs) are suggested to possess a highly plastic ability to differentiate into seve......
OBJECTIVE:To evaluate whether Shenfu injection(SFI)protects against cardiac myocyte injury induced by Fupian injection(F......
The present study examined cardiac myocytecontractile and Ca2+ transient responses to insulin duringsimulated ischemia/r......
INHIBITORY EFFECT OF TRIMETAZIDINE ON CARDIAC MYOCYTE APOPTOSIS IN RABBIT MODEL OF ISCHEMIA-REPERFUS
The present study was undertaken to determine the effect of trimetazidine (TMZ) on ischemia/reperfusion-induced my-ocyte......
Inhibitory effect of antisense oligodeoxynucleotide to p44/p42 MAPK on angiotensin Ⅱ-induced hypertr
AIM: To explore the inhibitory effect of antisense oligonucleotide (ODN) to mitogen activated protein kinase (MAPK) on c......
有丝分裂原激活的蛋白激酶(mitogen-activatedprotein kinase,MAPK)通路是联结心肌肥厚外源和内源信号的重要成分。细胞外信号调控......
目的:证实人心房组织有SK2的存在。方法:RT-PCR和western-blot分别检测SK2的mRNA和蛋白。结果:RT-PCR检测到人心房组织中存在SK2的......
Intermittent hypobaric hypoxia protects the heart against ischemia-reperfusion injury through activa
AIM:Cumulated evidence have shown that intermittent hypobaric hypoxia(IHH)can protect the heart against ischemia-reper-f......
Aim:To investigate the role of norepinephrine in the development of short-termmyocardial hibernation.Methods:Hearts wer......
Reactive oxygen species(ROS) plays a key role in human heart diseases. Glutathione peroxidase(GPX) functions as an antio......
充血性心力衰竭(congestive heart failure,CHF)是心肌梗死的并发症,严重影响人类的健康,尽管目前药物治疗CHF的效果已经有很大提......
Characterization and Differentiation into Adipocytes and Myocytes of Porcine Bone Marrow Mesenchymal
该文从挂篮荷载计算、施工流程、支座及临时固结施工、挂篮安装及试验、合拢段施工、模板制作安装、钢筋安装、混凝土的浇筑及养生......
Hepatocyte growth factor combined with insulin like growth factor-1 improves expression of GATA-4 in
Background In a suitable microenvironment,bone marrow mesenchymal stem cells(BMSCs)can transdifferentiate into myocardia......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的初步探讨二甲基甲酰胺(dimethylformamide,DMF)是否通过线粒体通路致H9c2心肌细胞凋亡及可能机制。方法 H9c2心肌细胞体外培养,......
Characterization and Differentiation into Adipocytes and Myocytes of Porcine Bone Marrow Mesenchymal
Bone marrow mesenchymal stem cells (BMSCs) could differentiate into various cell types including adipocytes and myocytes......
Hepatocyte growth factor combined with insulin like growth factor-1 improves expression of GATA-4 in
Background In a suitable microenvironment,bone marrow mesenchymal stem cells(BMSCs)can transdifferentiate into myocardia......
目的探讨氯沙坦对心功能正常的非梗阻性肥厚型心肌病(NOHCM)患者心肌肥厚程度的影响。方法根据有无使用氯沙坦,将41例心功能正常的......
目的:探讨内皮素-1(ET-1)对大鼠心肌细胞正性肌力作用的细胞内机制.方法:将离子敏感性荧光指示剂indo-1和SNARF-1载入大鼠心室肌细......
采用电子显微镜技术,研究了苦皮藤素Ⅳ对东方粘虫(Mythimna separata Walker)肌肉系统的影响.电镜观察发现,苦皮藤素Ⅳ对东方粘虫......
目的研究吗啡预处理对心肌的保护作用以及格列苯脲对其的影响。方法采用新生大鼠的原代心肌培养细胞作为研究对象,将培养心肌细胞......
观察缺氧-复氧对大鼠心室肌细胞的损伤及川芎嗪的保护作用。方法 在缺氧-复氧条件下,测量对照组和不同浓度川芎嗪组对杆形心肌细胞百......
目的:观察非酶糖化抑制剂-氨基胍(AG)对糖尿病大鼠心肌细胞凋亡的影响.方法:54只SD大鼠分为12周对照组(8只),24周对照组(10只);糖......
体外研究表明:血管紧张素Ⅱ(AngⅡ)可引起心肌细胞肥大,但其信息传递途径尚不清楚。本文通过^3H-Leu掺入率的测定与RNA狭线杂交技术,初步探讨了AngⅡ受体......
目的:探讨促红细胞生成素(EPO)发挥心肌细胞保护作用的可能分子机制。方法:采用流式细胞仪检测各组心肌细胞的存活率、凋亡率和坏死率......
目的探讨Salubrinal对衣霉素诱导的乳鼠原代心肌细胞凋亡的保护作用及机制。方法采用消化贴壁法获得乳鼠原代心肌细胞,分别给与不......
目的:探讨成纤维细胞生长因子21(FGF21)在内质网应激(ERS)诱导心肌细胞凋亡中的保护作用及其作用机制。方法:以pc DNA4为基因载体,......
目的:探讨细胞内pH(pHi)改变对心肌细胞内Ca^2+浓度([Ca^2+]i)和细胞长度的影响。方法:心肌细胞内分别灌注20mmol/L丙酸钠和15mmol/L ......
目的:探讨急性心肌梗死(AMI)后兔心室肌细胞L型钙电流的变化及黄芪的影响.方法:兔开胸左前降支结扎造成AMI,腹腔注射黄芪2ml/只......
用Fura-2/AM技术直接观察前胡丙素(Pra-C)对培养大鼠心室肌细胞内游离钙的影响。结果显示Par-C浓度为0.1-1.0μmol.L^-1可明显抑CaCL,高K^+和Bay K8644引起[Ca^2+]i增加,并且有剂量一效应关系,对ouabain引......
本实验采用分离的SD大鼠心室肌细胞,以Fura-2AM荧光指示剂负载,检测心肌细胞内游离钙浓度(Ca^2+)变化。探讨亮啡肽(LEK)对(Ca^2+)的作用及其机制。实验结果:LEK(60μmol/L)能升高......
利用新生大鼠心室成纤维细胞条件培养液孵育心肌细胞,证实成纤维细胞条件培养液能明显增大心肌细胞的表面积,增加心肌细胞的蛋白含量......
目的:研究5-氮杂胞苷(5-azacytidine,5-aza)诱导体外骨髓间充质干细胞(marrow measenchymal stem cells,MSCs)向心肌细胞发展的作用及其机......
目的 一定时间的心肌缺血可诱导心肌细胞凋亡,而缺血后再灌注损伤对心肌细胞凋亡影响尚未阐明。方法 将50只SD大鼠随机分为5组,以TUN......
目的:探讨Na^+/H^+交换器(NHE)在缺氧性肺动脉高压大鼠模型肺动脉平滑肌细胞中的表达。方法:30只Wistar大鼠,随机分为3组,分别为:正常对照组,缺氧3周组和缺氧8周组......